Organization & Processes

The Laboratory for Innovation Science at Harvard (LISH) conducts research on how labs operate, including the process researchers take in developing new products and ideas and how best to capitalize on successes and bring solutions out of the lab and into commercial use.

Key Questions

Question

What are the drivers of productivity in science and engineering laboratories?

Question

How can crowds be integrated with traditional R&D functions in companies and academic labs?

Question

What are the biases in the processes of evaluating innovative ideas? How can they be overcome?

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What are the predictors of breakthrough success for innovative scientific ideas?

Question

How can technology commercialization be accelerated from academic and government labs?

 

Projects in this research track are most directly associated with the Managing R&D Labs & Organizations and Technology Translation areas of application, which include experiments around grant applications and scientific awards, the development of a massive open online course on technology translation, and the integration of crowds into academic labs. See below for more information on each of the individual projects in this research track.

Related Publications

Karim R. Lakhani, Johann Fuller, Volker Bilgram, and Greta Friar. 2014. Nivea (A). Harvard Business School Case. Harvard Business School. Publisher's VersionAbstract

The case describes the efforts of Beiersdorf, a worldwide leader in the cosmetics and skin care industries, to generate and commercialize new R&D through open innovation using external crowds and "netnographic" analysis. Beiersdorf, best known for its consumer brand Nivea, has a rigorous R&D process that has led to many successful product launches, but are there areas of customer need that are undervalued by the traditional process? A novel online customer analysis approach suggests untapped opportunities for innovation, but can the company justify a launch based on this new model of research?

Michael L. Tushman, Hila Lifshitz-Assaf, and Kerry Herman. 2014. Houston, We Have a Problem: NASA and Open Innovation (B). Harvard Business School Case. Harvard Business School. Publisher's VersionAbstract
Jeff Davis, director of Space Life Sciences Directorate at NASA, has been working for several years to raise awareness amongst scientists and researchers in his organizations of the benefits of open innovation as a successful and efficient way to collaborate on difficult research problems regarding health and space travel. Despite a number of initiatives, SLSD members have been skeptical about incorporating the approach into their day-to-day research and work, and have resisted Davis's and his strategy team's efforts. The (A) case outlines these efforts and the organization members' reactions. The (B) case details what Davis and the SLSD strategy team learned, and how they adapted their efforts to successfully incorporate open innovation as one of many tools used in collaborative research at NASA.
Michael L. Tushman, Hila Lifshitz-Assaf, and Kerry Herman. 2014. Houston, We Have a Problem: NASA and Open Innovation (A). Harvard Business School Case. Harvard Business School. Publisher's VersionAbstract
Jeff Davis, director of Space Life Sciences Directorate at NASA, has been working for several years to raise awareness amongst scientists and researchers in his organizations of the benefits of open innovation as a successful and efficient way to collaborate on difficult research problems regarding health and space travel. Despite a number of initiatives, SLSD members have been skeptical about incorporating the approach into their day-to-day research and work, and have resisted Davis's and his strategy team's efforts. The (A) case outlines these efforts and the organization members' reactions. The (B) case details what Davis and the SLSD strategy team learned, and how they adapted their efforts to successfully incorporate open innovation as one of many tools used in collaborative research at NASA.
Karim R. Lakhani, Katja Hutter, Stephanie Healy Pokrywa, and Johann Fuller. 2013. Open Innovation at Siemens. Harvard Business School Case. Harvard Business School. Publisher's VersionAbstract

The case describes Siemens, a worldwide innovator in the Energy, Healthcare, Industry, and Infrastructure & Cities sectors, and its efforts to develop and commercialize new R&D through open innovation, including internal and external crowdsourcing contests. Emphasis is placed on exploring actual open innovation initiatives within Siemens and their outcomes. These include creating internal social- and knowledge-sharing networks and utilzing third party platforms to host internal and external contests. Industries discussed include energy, green technology, infrastructure and cities, and sustainability. In addition, the importance of fostering a collaborative online environment and protecting intellectual property is explored.

Eva C. Guinan, Karim R. Lakhani, and Kevin J. Boudreau. 2013. “Experiments in Open Innovation at Harvard Medical School.” MIT Sloan Management Review 54 (3). Publisher's VersionAbstract

This article examines an experiment in open innovation applied to scientific research on Type 1 diabetes at Harvard Medical School. In the traditional research process in academic medicine, a single research team typically carries through each stage of the process — from generating the idea to carrying out the research and publishing the results. Harvard Catalyst, a pan-Harvard agency with a mission to speed biomedical research from the lab to patients' bedsides, modified the traditional grant proposal process as an experiment in bringing greater openness into every stage of research. Participation was successfully extended to nontraditional actors. With support from Dr. William Chin, the executive dean for research at Harvard Medical School and a former vice president of research at Eli Lilly (an early adopter of open innovation), Harvard Catalyst started with the front end of the innovation system by opening up the process of generating research questions. Instead of focusing on identifying individuals who might tackle a tough research problem, Harvard Catalyst wanted to allow an open call for ideas in the form of a prize-based contest to determine the direction of the academic research. This might lead to potentially relevant questions not currently under investigation or largely ignored by the Type 1 diabetes research community. Harvard Catalyst partnered with the InnoCentive online contest platform to initiate the idea generation process. Participants had to formulate well-defined problems and/or hypotheses to advance knowledge about Type 1 diabetes research in new and promising directions. In the end, 150 new hypotheses and research pathways were proposed. Teams were invited to propose projects on the 12 most promising of these; today, seven teams are carrying out the research. The Harvard Catalyst experience suggests that open-innovation principles can be adopted even within a well-established and experienced innovation-driven organization.

Karim R. Lakhani, Kevin J. Boudreau, Po-Ru Loh, Lars Backstrom, Carliss Y. Baldwin, Eric Lonstein, Mike Lydon, Alan MacCormack, Ramy A. Arnaout, and Eva C. Guinan. 2013. “Prize-based Contests Can Provide Solutions to Computational Biology Problems.” Nature Biotechnology, 31, 2, Pp. 108-111. Publisher's VersionAbstract

In summary, we show that a prize-based contest on a commercial platform can effectively recruit skilled individuals to apply their knowledge to a big-data biomedical problem. Deconstruction and transformation of problems for a heterogeneous solver community coupled with adequate data to produce and validate results can support solution diversity and minimize the risk of sub-optimal solutions that may arise from limited searches. In addition to the benefits of generating new knowledge, this strategy may be particularly useful in situations where the computational or algorithmic problem, or potentially any science problem, represents a barrier to rapid progress but where finding the solution is not itself the major thrust of the investigator’s scientific effort. The America Competes Act passed by the US Congress provides funding agencies with the authority to administer their own prize-based contests and paves the way for establishing how grant recipients might access commercial prize platforms to accelerate their own research.